Chaperones and the maturation of steroid hormone receptor complexes

Please note : It is the responsibility of group leaders and chaperones to enforce these guidelines with their teens. Conference staff and volunteers will not personally address modesty with participants unless there is a gross violation. Steubenville Partners

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The investigation of chaperones has a long history. [25] The term "molecular chaperone" appeared first in the literature in 1978, and was invented by Ron Laskey to describe the ability of a nuclear protein called nucleoplasmin to prevent the aggregation of folded histone proteins with DNA during the assembly of nucleosomes. [26] The term was later extended by R. John Ellis in 1987 to describe proteins that mediated the post-translational assembly of protein complexes. [27] In 1988, it was realised that similar proteins mediated this process in both prokaryotes and eukaryotes. [28] The details of this process were determined in 1989, when the ATP-dependent protein folding was demonstrated in vitro . [29]

Chaperones and the maturation of steroid hormone receptor complexes

chaperones and the maturation of steroid hormone receptor complexes

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