Steroid side effects in cats

Corticosteroid myopathy presents as weakness and wasting of the proximal limb and girdle muscles and is generally reversible following cessation of therapy.

Corticosteroids inhibit intestinal calcium absorption and increase urinary calcium excretion leading to bone resorption and bone loss. Bone loss of 3% over one year has been demonstrated with prednisolone 10 mg per day. Postmenopausal females are particularly at risk for loss of bone density. Sixteen percent of elderly patients treated with corticosteroids for 5 years may experience vertebral compression fractures. One author reported measurable bone loss over two years in women on concomitant therapy with prednisolone mg per day and tamoxifen. [ Ref ]

These eye drops and ointments contain a combination of a steroid and one or more types of antibiotic for treatment of infection and inflammation of the eye. The steroid reduces inflammation while the antibiotic treats or prevents infection which may be the cause of the infection. Examples of steroids that are used in these eye drops are hydrocortisone, loteprednol, prednisolone, and dexamethasone . Examples of antibiotics used in these formulations include tobramycin, neomycin, bacitracin, polymixin B, and gentamycin. These antibiotics have different mechanisms of action and two or three may be combined in one formulation.

Steroid side effects in cats

steroid side effects in cats

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